Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • BildiriAçık Erişim2026
    Explainable Attention-Guided Swin Transformer Networks for Brain Tumor Segmentation from 3D MRI

    Ranjbarzadeh, Ramin; Keles, Ayse; Anari, Shokofeh; Zarbakhsh, Payam; Bendechache, Malika; Atulya K., N.; Dharm Singh, J.; Durgesh Kumar, M.; Joshi, A.

    This research presents a two-stage cascaded 3D segmentation approach designed for accurate brain tumor delineation in multimodal MRI data. The design incorporates a Swin Transformer backbone alongside Atrous Spatial Pyramid Pooling (ASPP) and Squeeze-and-Excitation (SE) blocks during the coarse segmentation phase to extract comprehensive, multi-scale contextual data. The second stage enhances the preliminary output with a class-wise attention decoder, which highlights tumor subregions—specifically, edema, necrotic core, and enhancing tumor—by masking the original input with the coarse predictions. The model employs a weighted Tversky loss to address the substantial class imbalance present in tumor segmentation tasks. Extensive experiments were executed on the BraTS 2020 dataset, incorporating preprocessing processes such as volume cropping and scaling to 128 × 128 × 128, with evaluation completed across training, validation, and test sets divided in a 70%–15%–15% ratio. The model exhibited exceptional accuracy in identifying tumor regions, with a Dice score of 0.99 for healthy tissue and above 0.5 for tumor subregions. The investigation of ROC curves and confusion matrices further substantiated the reliability of the forecasts. To improve model transparency, layer-wise Grad-CAM heatmaps were produced, illustrating the transition of attention from general background in first levels to concentrated tumor localization in subsequent layers. The proposed method attains competitive segmentation performance while providing a more interpretable and therapeutically pertinent answer. The results underscore the efficacy of integrating coarse-to-fine cascaded architectures with transformer-based encoders and attention-driven refinement for brain tumor segmentation.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2026
    Explainable deep learning framework for brain tumor segmentation using vision transformer and conditional random fields

    Safarpour, Homayoun; Sadeghi, Soroush; Zarbakhsh, Payam; Kamsari, Mohammadreza; Kia, Marjan; Ranjbarzadeh, Ramin

    Brain tumor segmentation is critical for accurate identification and treatment planning. However, delineating intricate tumor areas like Edema, Tumor Core, and Enhancing Tumor remains challenging owing to diversity in dimensions, morphology, and delineation. This introduces a novel deep learning model integrating a pretrained Vision Transformer (ViT) for global context representation, Atrous Spatial Pyramid Pooling (ASPP) in both encoder and merging stages, and ReLU6. Additionally, attention mechanisms and Conditional Random Fields (CRF) were incorporated for refining feature emphasis and segmentation boundaries. The model was trained and tested on the BraTS 2020 dataset and compared with state-of-the-art methods. The suggested model obtained the highest Dice coefficients across all tumor regions, with improvements of up to 4% over nnU-Net and SwinBTS in the Enhancing Tumor and Edema region. Grad-CAM heatmaps illustrated the model’s proficiency in precisely identifying tumor areas, hence enhancing the interpretability of predictions. The incorporation of multi-scale feature extraction, attention mechanism, and global context representation markedly improved segmentation accuracy and interpretability. The findings underscore the proposed model’s capacity to enhance clinical processes and establish a standard for brain tumor segmentation tasks. Future endeavors involve testing on varied datasets and investigating lightweight structures for real-time applications.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • BildiriYalnız künye2024
    Combined Surgical and Orthodontic Treatment for Eruption of the Impacted Premolar Due to a Dentigerous Cyst

    Özant, Ahmet; Ersalıcı, İsmet; Temelci, Ali; Minervini, Giuseppe; Badnjević, A.; Gurbeta Pokvić, L.

    The dentigerous cyst (DC) is a prevalent developmental odontogenic cyst, characterized by an epithelial-lined pathological cavity that is closely related to an unerupted or impacted tooth crown. This cyst is predominantly observed in third molars, maxillary canines, and premolars, and is typically asymptomatic. However, over time bone resorption, minimal bone expansion and tooth displacement may occur. In this case, a 14-year-old female patient was referred to our clinic for a routine radiographic and clinical examination. Radiographic examination revealed an impacted mandibular second premolar tooth and a cystic appearance around the crown of an impacted premolar tooth. CBCT slices showed that the tooth had a close proximity to the mental foramen. After a fine needle aspiration biopsy, the histopathological examination showed that the lesion was an odontogenic cyst which was latterly reported as a dentigerous cyst with the anamnesis and radiographic features. Surgery was planned for the patient under local anesthesia. The visible part of the cyst was removed, the crown of the tooth was exposed and an orthodontic button was placed. The orthodontic force was applied 3 weeks following the surgery to extrude the tooth. After 10 months, the tooth had erupted to the occlusion. Since dentigerous cysts attach to the tooth at the enamel-cementum junction, they can be treated by occlusion of the related tooth. It has been shown that successful treatment can be performed with a conservative approach with surgical and orthodontic planning. In this way, since there is no need for extraction and prevent a possible nerve injury.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • Dergi
    Lecture Notes in Networks and Systems
  • Dergi
    Multimedia Systems
  • Dergi
    IFMBE Proceedings