Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleYalnız künye2026
    Impact of ROI size on fractal dimension values in radiographs using a novel ROI selection method

    Yavuz, Esra; Tunc, Selmi

    Objective: This study aimed to evaluate the effect of various sizes of regions of interest (ROIs) on fractal dimension (FD) in the evaluation of trabecular bone structure in dental radiographic images. Materials and methods: This study included 12 sheep hemimandibles. One set of digital images was obtained from each hemimandible using either periapical radiography, panoramic radiography, or cone-beam computed tomography (CBCT). Fractal analysis (FA) was conducted using ImageJ 1.3 software with the box-counting method on small, medium, and large ROIs obtained from each image, using a novel ROI selection method. Comparisons of FD values obtained from the three different ROI sizes were conducted within each radiographic image using repeated-measures ANOVA. Post hoc pairwise comparisons were performed with Bonferroni correction. Data were analyzed using Jamovi 1.6.23. Statistical significance was accepted as p < 0.05. Results: In periapical radiography, the FD values ​​obtained in small, medium, and large ROI sizes were 1.60 ± 0.02, 1.60 ± 0.01, and 1.65 ± 0.01, respectively (p < 0.001). In panoramic radiography, they were 1.45 ± 0.04, 1.71 ± 0.02, and 1.59 ± 0.01, respectively (p < 0.001), and in CBCT, they were 0.76 ± 0.07, 1.21 ± 0.04, and 1.48 ± 0.04, respectively (p < 0.001). Conclusions: The study demonstrates that FD is affected by the ROI size.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2026
    Evaluation of the effects of A-PRF and oral dexamethasone use on postoperative complications in third molar extraction: a split-mouth randomized-controlled trial

    Elbahisi, Youssef Hazza Mohamed; Keskin Tunç, Serap; Başkan Önal, Aslı; Baydar, Sava

    Background: The aim of this study was to compare the effects of advanced platelet-rich-fibrin (A-PRF) and oral dexamethasone on postoperative complications in patients undergoing impacted mandibular third molar extraction. Methods: This split-mouth, prospective, randomized-controlled study involved bilateral extraction of impacted mandibular third molars. A-PRF was applied to the extraction socket on one side, while postoperative oral dexamethasone was prescribed for the other side. Data were collected on pain, edema, trismus, and analgesic consumption. Intra-group and inter-group comparisons were performed. The Visual Analog Scale (VAS) was used for pain assessment. The patients were given a form to record their postoperative analgesic use. Pain assessments were conducted at postoperative 3, 6, 9, 12, 24 h, and on Days 2, 3, 4, 5, 6, 7, 14, and 30. Maximum interincisal distance was measured for trismus evaluation, while facial measurements between specific points were taken for edema assessment. Trismus and edema measurements were conducted on postoperative Days 2, 7, 14, and 30. Results: This study included 30 patients with bilateral impacted mandibular third molars (total of 60 extractions). The VAS scores were significantly lower on the side treated with oral dexamethasone compared to the A-PRF side at all measurement times (p < 0.01). Considering edema evaluation, measurements were similar between both sides at all time points except on Day 2, when the A-PRF side showed significantly higher values (p = 0.001 and p < 0.01). For trismus evaluation, maximum interincisal distance was significantly greater on the oral dexamethasone side on Days 2 and 7 compared to the A-PRF side (p = 0.001 and p < 0.01). Analgesic consumption was significantly higher in the A-PRF group than in the oral dexamethasone group at all measured time points between 12 h and Day 7 (p < 0.01). Conclusion: Oral dexamethasone appeared to be more effective than A-PRF in reducing postoperative complications. However, no significant difference was observed between the two groups in edema on Days 7, 14, and 30. Although not as effective as oral dexamethasone, A-PRF, being an autologous product with no side effects, can still be considered for reducing complications following impacted tooth extraction. Trial Registration: The study was retrospectively registered at ClinicalTrials.gov with the number of NCT06823934, Registration date 02 June 2025.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2023
    Factors influencing the level of stigma in Parkinson's disease in western Turkey

    Demiryurek, E; Demiryurek, BE

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2023
    Sustaining the Earth: Unraveling the Synergy of Workplace Spirituality, Responsible Leadership, and Pro-Environmental Behavior in Pakistan's SMEs

    Shah, Syed Haider Ali; Fahlevi, Mochammad; Jamshed, Kamran; Aman, Nida; Rafiq, Nosheen; Jermsittiparsert, Kittisak; Aljuaid, Mohammed

    Purpose: The purpose of this research is to investigate the synergistic impact of workplace spirituality (WPS), responsible leadership (RL), and pro-environmental behavior (PEB) within the context of Pakistan's Small and Medium Enterprises (SMEs) along with the mediating mechanism of Affective commitment (AC).Methods: Our study utilizes structural equation modeling (SEM) to analyze survey data collected from 390 employees within Pakistani SMEs. We develop a single unified framework to test the hypothesized relationships between RL, PEB, and AC as a mediator. Results: Our results unveil significant positive relationships between WPS, RL, and PEB. Our findings endorse both the direct connections between WPS, RL, and PEB, as well as the mediating mechanisms through AC. This study offers novel insights into the influence of PEB in the context of Pakistan's SMEs.Conclusion: The research significantly contributes to the existing literature by examining WPS, RL, PEB, and AC in the context of Pakistan's SMEs. The study's conclusions emphasize the potential benefits of integrating WPS and RL into business practices to encourage PEB. Additionally, we discuss the limitations of our research and suggest future avenues for further exploration in this vital area of sustainable business management.

    • SDG 8 · İnsana Yakışır İş ve Ekonomik Büyüme
  • MakaleAçık Erişim2023
    Access Cavity Preparation and Localization of Root Canals Using Guides in 3D-Printed Teeth with Calcified Root Canals: An In Vitro CBCT Study

    Kamburoğlu, Kıvanç; Sönmez, Gül; Koç, Cemre; Yılmaz, Funda; Tunç, Osman; Isayev, Abulfaz

    Pulp canal obliteration (PCO) is a significant complication in endodontics that can occur due to various factors. Cone beam computed tomography (CBCT) is a useful diagnostic tool for identifying root canal anatomy and variations, and guided endodontics is emerging as an alternative treatment solution for teeth with partially or entirely obliterated pulpal canals. However, the accuracy of CBCT-guided 3D-printed guides on different materials and layer thicknesses is not well understood. Therefore, this study aimed to evaluate the accuracy of guides prepared using CBCT images on 3D-printed teeth with stereolithography (SLA) using three different materials and two different layer thicknesses. This study found that 3D-printed guides were accurate and reliable for accessing 3D-manufactured obliterated teeth and reaching the apical area. No significant differences in distance or angle measurements were found when different guide materials were used, suggesting that materials can be selected based on availability and cost. These findings contribute to the knowledge base regarding the effectiveness of 3D printing technology in guided endodontics and can help to identify the most suitable materials and techniques for this application.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2023
    Cone-beam-computed tomography evaluation of mandibular nutrient canals in patients with periodontal diseases

    Tumer, H.; Orhan, K.; Aksoy, S.; Berberoglu, A.

    Background and Aim: The aim of this study was to evaluate radiographically the prevalence of mandibular nutrient canals (NCs) in patients with/without periodontal bone loss with aging and to correlate the number of NCs with the severity of bone loss using cone-beam-computed tomography (CBCT). Patients and Methods: CBCT examinations of 208 patients were evaluated retrospectively of all patients, 114 had periodontal bone loss, whereas 94 patients were control subjects. Alveolar bone loss investigations were performed according to the Progressive Rate Index. Results: NCs were observed in 55% of the control group and 86% of the periodontitis patients. NCs were more prevalent in the elderly age group with periodontal bone loss. In the study group, the NCs were statistically more frequent than in the control subjects (P > 0.05). Conclusion: Statistical analysis showed a significant difference between the age groups and the prevalence of NCs increased in patients with periodontal alveolar bone loss with aging (P < 0.05).

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2023
    Does α-lipoic acid therapeutically effective against experimentally induced-acute pulpitis in rats?

    Kermeoğlu, Fatma; Sayıner, Serkan; Şehirli, Ahmet Özer; Savtekin, Gökçe; Aksoy, Umut

    The purpose of the study was to investigate the therapeutic effects of α-lipoic acid (ALA) on an induced-acute pulpitis model in rats. Twenty-four Wistar albino rats were randomly divided into three groups: control, induced-acute pulpitis (PULP) and PULP + ALA groups. In the PULP and PULP + ALA groups, the crowns of the maxillary left incisors were removed horizontally. All exposed pulp tissues were treated with 5 µL LPS solution. In the PULP + ALA group, the rats were treated intraperitoneally with a single dose of ALA (100 mg/kg). The rats were sacrificed 24 h after pulp injury, and the trunk blood and pulp samples were collected and then determined using ELISA assay kits. TNF-α, IL-1β, MMP-1 and MMP-2 levels in the serum and pulp tissues were considerably higher in the PULP group than the control group (p < 0.01–0.001). In the PULP + ALA group, TNF-α, IL-1β, MMP-1 and MMP-2 levels in the serum and pulp tissues decreased significantly compared to the PULP group (p < 0.05–0.001). ALA decreases pro-inflammatory mediators and proteolytic enzymes, which might relieve acute inflammation.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2022
    Clinical comparison of intraoral CMOS and PSP detectors in terms of time efficiency, patient comfort, and subjective image quality

    Kamburoğlu, K; Samunahmetoğlu, E; Eratam, N; Sönmez, G; Karahan, S

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2022
    Perception towards vaccine effectiveness in controlling COVID-19 spread in rural and urban communities: A global survey

    Marzo, Roy R.; Shrestha, Rajeev; Sapkota, Binaya; Acharya, Swosti; Shrestha, Nita; Pokharel, Mandip; Ahmad, Absar; Patalinghug, Mark E.; Rahman, Farzana; Salim, Zahir R.

    IntroductionSeveral studies exhibited varying reports of perception toward vaccine effectiveness, vaccine hesitancy, and acceptance of COVID-19 vaccines. As this fluctuated with evidence generation, this study explored the perception toward vaccine effectiveness in rural and urban communities among various countries. MethodsA cross-sectional study was conducted online from April to August 2021 using convenience sampling among people from different countries approved by the Asia Metropolitan University Medical Research and Ethics. We adapted the questionnaire from the World Health Organization's (WHO) survey tool and guidance on COVID-19. The logistic regression models were performed to show perception toward vaccine effectiveness. ResultsA total of 5,673 participants responded to the online survey. Overall, 64% of participants agreed that the vaccine effectively controlled viral spread, and 23% agreed that there was no need for vaccination if others were vaccinated. Males had 14% higher odds of believing that there was no need for vaccination. Less social media users had 39% higher odds of developing the belief that there is no need for vaccination than all other people vaccinated. ConclusionPeople's perceptions toward vaccine acceptance have fluctuated with the information flow in various social media and the severity of COVID-19 cases. Therefore, it is important that the current scenario of peoples' perception toward vaccine acceptance and determinants affecting the acceptance are explored to promote the vaccination approach against COVID-19 prevention and transmission effectively.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2022
    Digital health literacy for COVID-19 vaccination and intention to be immunized: A cross sectional multi-country study among the general adult population

    Marzo, Roy Rillera; Su, Tin Tin; Ismail, Roshidi; Htay, Mila Nu Nu; Essar, Mohammad Yasir; Chauhan, Shekhar; Patalinghug, Mark E. E.; Kucuk Bicer, Burcu; Respati, Titik; Fitriyana, Susan

    IntroductionIt is clear that medical science has advanced much in the past few decades with the development of vaccines and this is even true for the novel coronavirus outbreak. By late 2020, COVID-19 vaccines were starting to be approved by national and global regulators, and across 2021, there was a global rollout of several vaccines. Despite rolling out vaccination programs successfully, there has been a cause of concern regarding uptake of vaccine due to vaccine hesitancy. In tackling the vaccine hesitancy and improving the overall vaccination rates, digital health literacy (DHL) could play a major role. Therefore, the aim of this study is to assess the digital health literacy and its relevance to the COVID-19 vaccination. MethodsAn internet-based cross-sectional survey was conducted from April to August 2021 using convenience sampling among people from different countries. Participants were asked about their level of intention to the COVID-19 vaccine. Participants completed the Digital Health Literacy Instrument (DHLI), which was adapted in the context of the COVID Health Literacy Network. Cross-tabulation and logistic regression were used for analysis purpose. ResultsOverall, the mean DHL score was 35.1 (SD = 6.9, Range = 12-48). The mean DHL score for those who answered Yes for support for national vaccination schedule was 36.1 (SD 6.7) compared to 32.5 (SD 6.8) for those who either answered No or Don't know. Factors including country, place of residence, education, employment, and income were associated with the intention for vaccination. Odds of vaccine intention were higher in urban respondents (OR-1.46; C.I.-1.30-1.64) than in rural respondents. Further, higher competency in assessing the relevance of online information resulted in significantly higher intention for vaccine uptake. ConclusionPriority should be given to improving DHL and vaccination awareness programs targeting rural areas, lower education level, lower income, and unemployed groups.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2022
    Effects of Bioresonance Application in Mice with Depressive-Like Behavior

    Cabıoğlu, M.T.; Aslan, E.L.; Karabey, S.Z.; Derdinne, G.G.; Akyüz, Ö.

    We studied the effects of bioresonance application on mice with depressive-like behavior induced by stress. A chronic mild stress model was developed in mice to monitor the effects of bioresonance application. After that, behavioral tests were performed. In the forced swimming test, the animals of the long bioresonance therapy demonstrated shorter group immobility time in comparison with mice of the stress group and stress group without therapy (animals of this group were sacrificed at the same time point as therapy groups in order to reveal a possibility of spontaneously recover in animals after stress without therapy). In the tail suspension test, a decrease in immobility time was observed in the long bioresonance therapy group, stress group, and stress without therapy group. These changes in behavioral test results can indicate that the application of bioresonance in mice can be an effective method of treating depressive-like behavior, but these conclusions should be supported by additional experimental studies and the use of different frequencies.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleAçık Erişim2021
    In vitro assessment of periapical lesions created in sheep mandibles by using high resolution ultrasonography and cone beam computed tomography

    Kamburoğlu, K; Çakmak, EE; Eratam, N; Sönmez, G; Karahan, S

    • SDG 3 · Sağlık ve Kaliteli Yaşam