Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Jermsittiparsert, Kittisak(6)
- Akkaya, Bülent(2)
- Aljuaid, Mohammed(2)
- Fahlevi, Mochammad(2)
- Ranjbarzadeh, Ramin(2)
- Wongsuwan, Navaporn(2)
- Zarbakhsh, Payam(2)
- Aksoy, S.(1)
- Aksoy, Umut(1)
- Akyüz, Ö.(1)
- Altinay, Fahriye(1)
- Altinay, Mehmet(1)
- Altinay, Zehra(1)
- Anari, Shokofeh(1)
- Aslan, E.L.(1)
- Atulya K., N.(1)
- Badnjević, A.(1)
- Baydar, Sava(1)
- Başkan Önal, Aslı(1)
- Bendechache, Malika(1)
- Berberoglu, A.(1)
- Cabıoğlu, M.T.(1)
- Chankoson, Thitinan(1)
- Chatchawanchanchanakij, Petcharaporn(1)
- Dagli, Gokmen(1)
- Derdinne, G.G.(1)
- Dharm Singh, J.(1)
- Durgesh Kumar, M.(1)
- Elbahisi, Youssef Hazza Mohamed(1)
- Ersalıcı, İsmet(1)
- Fırat, Hicran Bayraktaroğlu(1)
- Gohwong, Srirath(1)
- Gurbeta Pokvić, L.(1)
- Hamid, Shaari Abd(1)
- Hamid, Shaari Abdul(1)
- Isayev, Abulfaz(1)
- Joshi, A.(1)
- Kamburoğlu, Kıvanç(1)
- Kamsari, Mohammadreza(1)
- Karabey, S.Z.(1)
Yayınlar
- BildiriYalnız künye2026Motivational Factors Affecting ELT Students' Use of ChatGPT Learning Outcomes in Preparing for Writing Tasks: A Mixed-Methods Study
Fırat, Hicran Bayraktaroğlu
The rapid rise of large language models such as ChatGPT is altering the landscape of English language education, influencing how learners approach writing, speaking, reading, and vocabulary work. Despite this shift, little is known about how English Language Teaching (ELT) majors—who must balance their roles as students and future educators—engage with these tools across different skill areas. To address this gap, the present study adopts a mixed-methods design to explore what motivates ELT students to use ChatGPT, drawing on a broad theoretical base that includes Technology Acceptance Model (TAM), the Unified Theory of Acceptance and Use of Technology (UTAUT), the Hedonic Motivation System Adoption Model (HMSAM), Self-Determination Theory (SDT), Flow Theory, and Cognitive Load Theory (CLT).The quantitative phase involved 100 randomly selected ELT students studying in the Turkish Republic of Northern Cyprus, who were invited through proportionate stratified random sampling across nine universities, while qualitative insights were gathered from interviews with 12 students recruited through purposive sampling. The findings indicate that intrinsic motivation, perceived usefulness, hedonic appeal, and ease of use strongly shape students’ intentions to work with ChatGPT. Writing stood out as the skill that students found most intrinsically and hedonically engaging, particularly because the tool helped reduce anxiety and support idea development. Speaking-related motivation was tied largely to affective benefits such as increased confidence and reduced communication apprehension. In contrast, reading and vocabulary use were driven more by practical, efficiency-oriented considerations. Interview data also revealed persistent ethical concerns, including plagiarism, over-dependence, and fairness in assessment, alongside professional-identity-driven reflections on the pedagogy and assessment. Overall, the study underscores the importance of strengthening AI literacy, establishing ethical guidelines, and rethinking assessment practices within ELT programs. It contributes a skill-specific, theoretically grounded perspective on how future English teachers navigate AI-mediated learning environments.
- MakaleYalnız künye2026Impact of ROI size on fractal dimension values in radiographs using a novel ROI selection method
Yavuz, Esra; Tunc, Selmi
Objective: This study aimed to evaluate the effect of various sizes of regions of interest (ROIs) on fractal dimension (FD) in the evaluation of trabecular bone structure in dental radiographic images. Materials and methods: This study included 12 sheep hemimandibles. One set of digital images was obtained from each hemimandible using either periapical radiography, panoramic radiography, or cone-beam computed tomography (CBCT). Fractal analysis (FA) was conducted using ImageJ 1.3 software with the box-counting method on small, medium, and large ROIs obtained from each image, using a novel ROI selection method. Comparisons of FD values obtained from the three different ROI sizes were conducted within each radiographic image using repeated-measures ANOVA. Post hoc pairwise comparisons were performed with Bonferroni correction. Data were analyzed using Jamovi 1.6.23. Statistical significance was accepted as p < 0.05. Results: In periapical radiography, the FD values obtained in small, medium, and large ROI sizes were 1.60 ± 0.02, 1.60 ± 0.01, and 1.65 ± 0.01, respectively (p < 0.001). In panoramic radiography, they were 1.45 ± 0.04, 1.71 ± 0.02, and 1.59 ± 0.01, respectively (p < 0.001), and in CBCT, they were 0.76 ± 0.07, 1.21 ± 0.04, and 1.48 ± 0.04, respectively (p < 0.001). Conclusions: The study demonstrates that FD is affected by the ROI size.
- MakaleAçık Erişim2026Evaluation of the effects of A-PRF and oral dexamethasone use on postoperative complications in third molar extraction: a split-mouth randomized-controlled trial
Elbahisi, Youssef Hazza Mohamed; Keskin Tunç, Serap; Başkan Önal, Aslı; Baydar, Sava
Background: The aim of this study was to compare the effects of advanced platelet-rich-fibrin (A-PRF) and oral dexamethasone on postoperative complications in patients undergoing impacted mandibular third molar extraction. Methods: This split-mouth, prospective, randomized-controlled study involved bilateral extraction of impacted mandibular third molars. A-PRF was applied to the extraction socket on one side, while postoperative oral dexamethasone was prescribed for the other side. Data were collected on pain, edema, trismus, and analgesic consumption. Intra-group and inter-group comparisons were performed. The Visual Analog Scale (VAS) was used for pain assessment. The patients were given a form to record their postoperative analgesic use. Pain assessments were conducted at postoperative 3, 6, 9, 12, 24 h, and on Days 2, 3, 4, 5, 6, 7, 14, and 30. Maximum interincisal distance was measured for trismus evaluation, while facial measurements between specific points were taken for edema assessment. Trismus and edema measurements were conducted on postoperative Days 2, 7, 14, and 30. Results: This study included 30 patients with bilateral impacted mandibular third molars (total of 60 extractions). The VAS scores were significantly lower on the side treated with oral dexamethasone compared to the A-PRF side at all measurement times (p < 0.01). Considering edema evaluation, measurements were similar between both sides at all time points except on Day 2, when the A-PRF side showed significantly higher values (p = 0.001 and p < 0.01). For trismus evaluation, maximum interincisal distance was significantly greater on the oral dexamethasone side on Days 2 and 7 compared to the A-PRF side (p = 0.001 and p < 0.01). Analgesic consumption was significantly higher in the A-PRF group than in the oral dexamethasone group at all measured time points between 12 h and Day 7 (p < 0.01). Conclusion: Oral dexamethasone appeared to be more effective than A-PRF in reducing postoperative complications. However, no significant difference was observed between the two groups in edema on Days 7, 14, and 30. Although not as effective as oral dexamethasone, A-PRF, being an autologous product with no side effects, can still be considered for reducing complications following impacted tooth extraction. Trial Registration: The study was retrospectively registered at ClinicalTrials.gov with the number of NCT06823934, Registration date 02 June 2025.
- BildiriAçık Erişim2026Explainable Attention-Guided Swin Transformer Networks for Brain Tumor Segmentation from 3D MRI
Ranjbarzadeh, Ramin; Keles, Ayse; Anari, Shokofeh; Zarbakhsh, Payam; Bendechache, Malika; Atulya K., N.; Dharm Singh, J.; Durgesh Kumar, M.; Joshi, A.
This research presents a two-stage cascaded 3D segmentation approach designed for accurate brain tumor delineation in multimodal MRI data. The design incorporates a Swin Transformer backbone alongside Atrous Spatial Pyramid Pooling (ASPP) and Squeeze-and-Excitation (SE) blocks during the coarse segmentation phase to extract comprehensive, multi-scale contextual data. The second stage enhances the preliminary output with a class-wise attention decoder, which highlights tumor subregions—specifically, edema, necrotic core, and enhancing tumor—by masking the original input with the coarse predictions. The model employs a weighted Tversky loss to address the substantial class imbalance present in tumor segmentation tasks. Extensive experiments were executed on the BraTS 2020 dataset, incorporating preprocessing processes such as volume cropping and scaling to 128 × 128 × 128, with evaluation completed across training, validation, and test sets divided in a 70%–15%–15% ratio. The model exhibited exceptional accuracy in identifying tumor regions, with a Dice score of 0.99 for healthy tissue and above 0.5 for tumor subregions. The investigation of ROC curves and confusion matrices further substantiated the reliability of the forecasts. To improve model transparency, layer-wise Grad-CAM heatmaps were produced, illustrating the transition of attention from general background in first levels to concentrated tumor localization in subsequent layers. The proposed method attains competitive segmentation performance while providing a more interpretable and therapeutically pertinent answer. The results underscore the efficacy of integrating coarse-to-fine cascaded architectures with transformer-based encoders and attention-driven refinement for brain tumor segmentation.
- MakaleAçık Erişim2026Explainable deep learning framework for brain tumor segmentation using vision transformer and conditional random fields
Safarpour, Homayoun; Sadeghi, Soroush; Zarbakhsh, Payam; Kamsari, Mohammadreza; Kia, Marjan; Ranjbarzadeh, Ramin
Brain tumor segmentation is critical for accurate identification and treatment planning. However, delineating intricate tumor areas like Edema, Tumor Core, and Enhancing Tumor remains challenging owing to diversity in dimensions, morphology, and delineation. This introduces a novel deep learning model integrating a pretrained Vision Transformer (ViT) for global context representation, Atrous Spatial Pyramid Pooling (ASPP) in both encoder and merging stages, and ReLU6. Additionally, attention mechanisms and Conditional Random Fields (CRF) were incorporated for refining feature emphasis and segmentation boundaries. The model was trained and tested on the BraTS 2020 dataset and compared with state-of-the-art methods. The suggested model obtained the highest Dice coefficients across all tumor regions, with improvements of up to 4% over nnU-Net and SwinBTS in the Enhancing Tumor and Edema region. Grad-CAM heatmaps illustrated the model’s proficiency in precisely identifying tumor areas, hence enhancing the interpretability of predictions. The incorporation of multi-scale feature extraction, attention mechanism, and global context representation markedly improved segmentation accuracy and interpretability. The findings underscore the proposed model’s capacity to enhance clinical processes and establish a standard for brain tumor segmentation tasks. Future endeavors involve testing on varied datasets and investigating lightweight structures for real-time applications.
- Kitap BölümüYalnız künye2025Balancing Innovation and Access: The Role of Intellectual Property in Healthcare
Wongmahesak, Kittisak
The pace of development in medical technology and pharmaceuticals is continuing to increase, making the impact that intellectual property (IP) has on healthcare even more important. The part of the chapter starts with types of IP patents, trademarks, copyrights, and trade secrets in healthcare research and development (R&D). On the one hand, it points out that strong IP protections spur innovation by enabling firms to capture a return on R&D spending, hence creating new issues about high drug prices and limited access among disadvantaged populations. The review also includes international trade agreements like the Trade-Related Aspects of Intellectual Property Rights (TRIPS) Agreement and Doha Declaration, which work for a strike of balance between IP rights and public health needs. The chapter advocates for the use of flexibilities within these frameworks such as compulsory licensing to improve access to life-saving treatments in public health emergencies. It concludes with a comparison of the ways in which IP is addressed in healthcare across nations illustrating that countries like India have found solutions where they prioritize public health and yet do not compromise on innovation. The chapter concludes with some ethical reflections on who should bear the cost in terms of lost profit when essential treatments are not accessible to those (M) CBs: patients, insurers, or pharm industries.
- MakaleYalnız künye2024Nexus between good governance and financial sustainability: evidence from microfinance sector of India
Maeenuddin, M.; Hamid, Shaari Abdul; Nassir, Annuar Md; Fahlevi, Mochammad; Aljuaid, Mohammed; Jermsittiparsert, Kittisak
Purpose: Microfinance emerged as an essential catalyst for socio-economic development and financial inclusion to reduce poverty. Microfinance institutions cannot meet their primary objective of poverty reduction if they are not sustainable financially. With the theoretical support of profit incentive theory, this paper aims to investigate the impact of organizational structure (OS), growth outreach (average loan per borrower [ALPB] and number of active borrowers), women empowerment (percentage of women borrowers [PWB]), liquidity, leverage and cost efficiency (cost per borrower) on the financial sustainability of microfinance providers (MFPs) in India and explore the possible moderating effect of the national governance indicators (NGIs). Design/methodology/approach: A financial sustainability index has been developed by using principal components analysis, including both conventional measures (return of assets and return on equity) and efficiency measures (operational self-sufficiency and financial self-sufficiency). Due to the existence of endogeneity and heteroskedasticity, this study uses two-step system generalized method of moments estimates to examine the relationships for a period of 2006 to 2018. Findings: The finding reveals that there is a strong significant relationship between financial sustainability and its influential factors. Organizatioanl Structure, loan size, women borrowers, Gross Domestic Products and inflation enhance the financial sustainability of India’s microfinance sector. However, a number of borrowers, liquidity, leverage and operating costs negatively affect the financial sustainability of MFPs of India. The estimates demonstrate that NGIs significantly moderate the association between financial sustainability and its influential factors. The NGIs negatively affect the positive impact of Organizatioanl Structure on financial sustainability. National governance increases the positive effect of loan size (ALPB) and reduces the negative effect of a number of borrowers and leverage on the financial sustainability of MFPs of India. However, NGIs negatively affect the positive relationship between Percentage of Women Borrowers and Financial sustainability of Microfinance Providers of India. Originality/value: To the best of the authors’ knowledge, this study is the first of its kind that incorporates all of the six dimensions of the National Governance Indicators (NGIs) and uses as a moderator. Secondly, a financial sustainability index has been developed for measuring the financial sustainability of Microfinance Providers (MFPs).
- MakaleAçık Erişim2024Measuring the Financial Sustainability and its Influential Factors in Microfinance Sector of Pakistan
Maeenuddin; Hamid, Shaari Abd; Nassir, Annuar MD; Fahlevi, Mochammad; Aljuaid, Mohammed; Jermsittiparsert, Kittisak
Financial sustainability is one of the major issues in the development process, particularly in developing countries. Microfinance started with two basic objectives of poverty reduction and women empowerment. However, unsustainable microfinance providers cannot assist the poor for a longer period of time, due to uncertainty about their existence. This study investigates that how financial sustainability of Pakistan’s microfinance sector is affected by various factors. A new financial sustainability index has been developed to measure the financial sustainability. Generalized Method of Moments (GMM) approach is employed to analyze the panel data from 34 Pakistani MFPs, yielding 344 MFI-years of observations from 2006 to 2018. The findings reveal that increase in loan size, female borrowers, liquidity, and leverage significantly enhances the financial viability of Microfinance Providers in Pakistan. However, the total borrowers and the operating cost per borrower negatively affect the financial sustainability of MFPs in Pakistan. MFIs needs to be financially independent, with less or no support from government or donor agencies. Financially sustainable MFPs contributes in the achievement of the 8 out of 17 Sustainable Development of Goals (2030 SDGs) of the United Nation. The data for 2018 onwards is seriously affected by COVID-19, which cannot be included in the current data set. Hence, researchers in future analyze the data from the pre-COVID-19 and post-COVID-19 periods to compare the analysis and examine the pandemic’s impact.
- BildiriYalnız künye2024Combined Surgical and Orthodontic Treatment for Eruption of the Impacted Premolar Due to a Dentigerous Cyst
Özant, Ahmet; Ersalıcı, İsmet; Temelci, Ali; Minervini, Giuseppe; Badnjević, A.; Gurbeta Pokvić, L.
The dentigerous cyst (DC) is a prevalent developmental odontogenic cyst, characterized by an epithelial-lined pathological cavity that is closely related to an unerupted or impacted tooth crown. This cyst is predominantly observed in third molars, maxillary canines, and premolars, and is typically asymptomatic. However, over time bone resorption, minimal bone expansion and tooth displacement may occur. In this case, a 14-year-old female patient was referred to our clinic for a routine radiographic and clinical examination. Radiographic examination revealed an impacted mandibular second premolar tooth and a cystic appearance around the crown of an impacted premolar tooth. CBCT slices showed that the tooth had a close proximity to the mental foramen. After a fine needle aspiration biopsy, the histopathological examination showed that the lesion was an odontogenic cyst which was latterly reported as a dentigerous cyst with the anamnesis and radiographic features. Surgery was planned for the patient under local anesthesia. The visible part of the cyst was removed, the crown of the tooth was exposed and an orthodontic button was placed. The orthodontic force was applied 3 weeks following the surgery to extrude the tooth. After 10 months, the tooth had erupted to the occlusion. Since dentigerous cysts attach to the tooth at the enamel-cementum junction, they can be treated by occlusion of the related tooth. It has been shown that successful treatment can be performed with a conservative approach with surgical and orthodontic planning. In this way, since there is no need for extraction and prevent a possible nerve injury.
- Kitap BölümüYalnız künye2023Antecedents to perceived usefulness of M-Commerce: An application of technology acceptance model
Jermsittiparsert, Kittisak; Wongsuwan, Navaporn; Akkaya, Bülent
The aim of this research work is to examine the originator which is affecting in Thailand the adoption of m-commerce (based on the behavioural intention). The usage of m-commerce has faced reluctance by the subscribers of mobile phone, which is in general the most anticipated challenge among both the developing and developed countries. Similarly, there are restricted empirical research work regarding to the m-commerce in Thailand. As a result, in the situation of developing countries (for instance, Thailand specially), very less numbers of research exist for the recognition of important variables for the m-commerce installation or estimating the m-commerce adoption variables. For explaining the behavioural targets of subscribers and for estimation generally the model that has been used is referred to as technology acceptance model (TAM). First, the factor subjective norms by the region of technology acceptance had contradictory outcomes and inconsistency to the behavioural target. In this study, we employed the Smart Partial Least Square Structural Equation Modelling version 3.2.6 as a data analysis technique. The response rate of the current study is 81%. The results have certainty that has established the presence of these associations between the users which implicated the significance of subjective norms in Thailand which were recognized. The personal opinion of usefulness, perceptions of attitude and easy usage to m-commerce are the important features towards the subjective norms which are the social impacts.
- MakaleAçık Erişim2023The role of industry 4.0 in sustainable supply chain: Evidence from the textile industry
Chatchawanchanchanakij, Petcharaporn; Jermsittiparsert, Kittisak; Chankoson, Thitinan; Waiyawuththanapoom, Phutthiwat
The objective of this study was to examine the role of Industry 4.0 in the sustainable supply chain (SSC). The relationship between Industry 4.0, data storage, data assessment, performance evaluation, data inquiry and SSC were examined. To achieve the study objective, the mediation effect of data storage, data assessment, performance evaluation and data inquiry between Industry 4.0 and SSC was examined. Employees of textile companies were selected for data collection in Indonesia. Results of the study highlighted that Industry 4.0 had a significant positive effect on SSC. Better implementation of Industry 4.0 showed a positive effect on SSC. In addition to this, Industry 4.0 had a positive effect on data storage, data assessment, performance evaluation and data inquiry. Finally, data storage, data assessment, performance evaluation and data inquiry had a positive effect on SSC.
- KitapYalnız künye2023Governmental power market-ing in the VU-CHAOS world
Jermsittiparsert, Kittisak; Gohwong, Srirath; Pavapanunkul, Shayut; Mahittichatkul, Nasaran
Governmental Power Market-Ing in the VU-CHAOS World is a thought-provoking book that explores the blended concepts of state governance, marketing, and management. This book offers a comprehensive examination of the dynamics and implications of governmental power in a rapidly changing world. Delve into this text to investigate the concept of government and its significance, as well as the rise of gerontocracy, where the elders exert influence over the state game, both in theory and practice. Further chapters explore topics such as the hidden agenda behind the development of government in governmental power marketing theory, the sources and status of government, strategies, and behavior of governments as buyers. The influences that shape governmental buying behavior and the implications for controlling governmental power are also examined. The book introduces criteria for assessing the effectiveness of these models and analyzes them for an understanding this complex field. The explorations of the intersection of power diffusion theory and power marketing security provides analytical frameworks for succeeding in strategic governmental power marketing. Readers will gain insights into future trends in government theory and practice, including strategic approaches for stateless players and net states. Case studies and comparative applications offer real-world examples and practical implications. Governmental Power Market-Ing in the VU-CHAOS World is an essential resource for academics, researchers, policymakers, and anyone interested in understanding the complex interplay between governmental power and market dynamics in today's evolving global landscape.
- Kitap BölümüYalnız künye2023Subjective norms and behavioural intention of E-banking adoption: Mediating role of perceived usefulness
Jermsittiparsert, Kittisak; Wongsuwan, Navaporn; Akkaya, Bülent
The study was planned to examine the impact of subjective norms on the behavioural intentions of Thai e-banking users. Additionally, the study has also examined the mediating role of perceived usefulness of e-banking in the relationship between the subjective norms and e-banking adoption. The subjective norms construct in this study was decomposed into societal descriptive and injunctive norms, and personal descriptive and injunctive norms. It is clear from the literature review that highly inconsistent findings were reported between perceived usefulness and subjective norms because of the contradiction in the findings obtained by the researchers. This occurred may be because trivial attention was given to the relationship between subjective norm and perceived usefulness. In current research, it is argued that there are many advantages of e-banking adoption which includes mobility, convenience and 24-hour accessibility anywhere anytime with no physical limitation of location as required in old-styled e-commerce. For that reason, it is hypothesized that people who believe that these advantages would result in the improvement in their performance are expected to create a positive environment for technology adoption. In the latest quantitative research development, the partial least squares (PLS) path modelling is considered to be unsuitable in determining the validity of the model. For this purpose, a two-step process is implemented in current research. The results of the present study, argued that e-banking is adopted voluntarily and the existence of high social norms in collectivist culture greatly influences the potential adopters' attitude and behaviour by the opinions of their significant others particularly in Thai context.
- MakaleAçık Erişim2023Access Cavity Preparation and Localization of Root Canals Using Guides in 3D-Printed Teeth with Calcified Root Canals: An In Vitro CBCT Study
Kamburoğlu, Kıvanç; Sönmez, Gül; Koç, Cemre; Yılmaz, Funda; Tunç, Osman; Isayev, Abulfaz
Pulp canal obliteration (PCO) is a significant complication in endodontics that can occur due to various factors. Cone beam computed tomography (CBCT) is a useful diagnostic tool for identifying root canal anatomy and variations, and guided endodontics is emerging as an alternative treatment solution for teeth with partially or entirely obliterated pulpal canals. However, the accuracy of CBCT-guided 3D-printed guides on different materials and layer thicknesses is not well understood. Therefore, this study aimed to evaluate the accuracy of guides prepared using CBCT images on 3D-printed teeth with stereolithography (SLA) using three different materials and two different layer thicknesses. This study found that 3D-printed guides were accurate and reliable for accessing 3D-manufactured obliterated teeth and reaching the apical area. No significant differences in distance or angle measurements were found when different guide materials were used, suggesting that materials can be selected based on availability and cost. These findings contribute to the knowledge base regarding the effectiveness of 3D printing technology in guided endodontics and can help to identify the most suitable materials and techniques for this application.
- MakaleAçık Erişim2023Cone-beam-computed tomography evaluation of mandibular nutrient canals in patients with periodontal diseases
Tumer, H.; Orhan, K.; Aksoy, S.; Berberoglu, A.
Background and Aim: The aim of this study was to evaluate radiographically the prevalence of mandibular nutrient canals (NCs) in patients with/without periodontal bone loss with aging and to correlate the number of NCs with the severity of bone loss using cone-beam-computed tomography (CBCT). Patients and Methods: CBCT examinations of 208 patients were evaluated retrospectively of all patients, 114 had periodontal bone loss, whereas 94 patients were control subjects. Alveolar bone loss investigations were performed according to the Progressive Rate Index. Results: NCs were observed in 55% of the control group and 86% of the periodontitis patients. NCs were more prevalent in the elderly age group with periodontal bone loss. In the study group, the NCs were statistically more frequent than in the control subjects (P > 0.05). Conclusion: Statistical analysis showed a significant difference between the age groups and the prevalence of NCs increased in patients with periodontal alveolar bone loss with aging (P < 0.05).
- MakaleYalnız künye2023Does α-lipoic acid therapeutically effective against experimentally induced-acute pulpitis in rats?
Kermeoğlu, Fatma; Sayıner, Serkan; Şehirli, Ahmet Özer; Savtekin, Gökçe; Aksoy, Umut
The purpose of the study was to investigate the therapeutic effects of α-lipoic acid (ALA) on an induced-acute pulpitis model in rats. Twenty-four Wistar albino rats were randomly divided into three groups: control, induced-acute pulpitis (PULP) and PULP + ALA groups. In the PULP and PULP + ALA groups, the crowns of the maxillary left incisors were removed horizontally. All exposed pulp tissues were treated with 5 µL LPS solution. In the PULP + ALA group, the rats were treated intraperitoneally with a single dose of ALA (100 mg/kg). The rats were sacrificed 24 h after pulp injury, and the trunk blood and pulp samples were collected and then determined using ELISA assay kits. TNF-α, IL-1β, MMP-1 and MMP-2 levels in the serum and pulp tissues were considerably higher in the PULP group than the control group (p < 0.01–0.001). In the PULP + ALA group, TNF-α, IL-1β, MMP-1 and MMP-2 levels in the serum and pulp tissues decreased significantly compared to the PULP group (p < 0.05–0.001). ALA decreases pro-inflammatory mediators and proteolytic enzymes, which might relieve acute inflammation.
- MakaleYalnız künye2022Effects of Bioresonance Application in Mice with Depressive-Like Behavior
Cabıoğlu, M.T.; Aslan, E.L.; Karabey, S.Z.; Derdinne, G.G.; Akyüz, Ö.
We studied the effects of bioresonance application on mice with depressive-like behavior induced by stress. A chronic mild stress model was developed in mice to monitor the effects of bioresonance application. After that, behavioral tests were performed. In the forced swimming test, the animals of the long bioresonance therapy demonstrated shorter group immobility time in comparison with mice of the stress group and stress group without therapy (animals of this group were sacrificed at the same time point as therapy groups in order to reveal a possibility of spontaneously recover in animals after stress without therapy). In the tail suspension test, a decrease in immobility time was observed in the long bioresonance therapy group, stress group, and stress without therapy group. These changes in behavioral test results can indicate that the application of bioresonance in mice can be an effective method of treating depressive-like behavior, but these conclusions should be supported by additional experimental studies and the use of different frequencies.
- MakaleYalnız künye2019Examination of connectivist theory in English language learning: The role of online social networking tool
Sozudogru, Oytun; Altinay, Mehmet; Dagli, Gokmen; Altinay, Zehra; Altinay, Fahriye
Purpose: The purpose of this paper is to examine the role of technology and online communication platforms in English language learning based on connectivist theory. Design/methodology/approach: Questionnaire and checklist were used to examine the role of online communication tools in the learning process. The data analysis was done with SPSS. Findings: Results showed that being involved in collaborative learning and dialogue increases connectivist knowledge, reflection and negotiation. Online communication tools can be used as an effective supplementary material for learning. Research limitations/implications: The limitation of this paper is that the number of participants was limited to 27. Practical implications: This paper gives insights on the use of language and technology integration. Social implications: New way of learning and language learning become essential for the pedagogy and learner in the higher education. Originality/value: The paper is original in its research context and gives a value to contribute new way of learning based on approach.